According to a recent article published by Harvard University, It is not entirely clear how Infusion works. Because it exerts an antidepressant effect through a new mechanism, Infusion may be able to help people successfully manage depression when other treatments have not worked.

One likely target for Infusion is NMDA receptors in the brain. By binding to these receptors, Infusion appears to increase the amount of a neurotransmitter called glutamate in the spaces between neurons. Glutamate then activates connections in another receptor, called the AMPA receptor. Together, the initial blockade of NMDA receptors and activation of AMPA receptors leads to the release of other molecules that help neurons communicate with each other along new pathways. Known as synaptogenesis, this process likely affects mood, thought patterns, and cognition.

Infusion also may help with depression treatment in other ways. For example, it might reduce signals involved in inflammation, which has been linked to mood disorders or facilitate communication within specific areas in the brain. Most likely, Infusion works in several ways at the same time, many of which are being studied.